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CDD-2212

STK33 Inhibitor

CDD-2212 is a selective STK33 inhibitor, exhibiting a dissociation constant (Kd) of 1.9 nM and an inhibitory concentration (IC50) of 999 nM. The compound demonstrates minimal off-target effects, showing IC50 values of 3223 nM for CLK1, 1555 nM for CLK2, 5884 nM for CLK4, and 1093 nM for RET. CDD-2212 is primarily utilized in research pertaining to contraception, facilitating the exploration of STK33’s role in reproductive biology.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3086535-52-3
Applications	STK33 Inhibitor
Formula	C₂₈H₂₆N₄O
Molecular Weight	434.53
SMILES	O=C(N1C[C@H](CC1)N(C)C)C2=CC=C3C(C(C#CC4=C(C5=CC=CC=C5)C=CC=C4)=NN3)=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.