Asnuciclib (CDKI-73)

Catalog No.: A21467
CDK9 inhibitor
CDKI-73 is a potent CDK9 inhibitor with Ki of 4 nM; shows selective toxicity to CLL cells(LD50=80 nM) versus normal B cell and normal CD34+ cell(LD50>20 uM).
Grouped product items
Product Name Price Stock Qty
Asnuciclib (CDKI-73) 5mg
$378.00
In stock
Asnuciclib (CDKI-73) 10mg
$651.00
In stock
Asnuciclib (CDKI-73) 50mg
$1,932.00
In stock
Asnuciclib (CDKI-73) 100mg
$3,864.00
In stock
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Biological Activity
Discription CDKI-73 is a potent CDK9 inhibitor with Ki of 4 nM; shows selective toxicity to CLL cells(LD50=80 nM) versus normal B cell and normal CD34+ cell(LD50>20 uM).
Targets
Target Value
Product Information
Catalog Num A21467
Formula C15H15FN6O2S2
Molecular Weight 394.45
CAS Number 1421693-22-2
SMILES CNC1=NC(C)=C(C2=C(F)C=NC(NC3=CC(S(=O)(N)=O)=CC=C3)=N2)S1
Synonyms CDKI73, CDKI 73, LS-007
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 77 mg/mL (195.2 mM)
Water Insoluble
Ethanol 1 mg/mL (2.53 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.35 mL 126.76 mL 253.52 mL
0.5 mM 5.07 mL 25.35 mL 50.7 mL
1 mM 2.54 mL 12.68 mL 25.35 mL
5 mM 0.51 mL 2.54 mL 5.07 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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