Fig. 1 · Structure
Documents & Downloads
Cedirogant
Cat. No.
A77567
CAS
2055496-11-0
RORγt Inverse Agonist
Cedirogant is an orally active inverse agonist of the retinoic acid receptor-related orphan receptor gamma-t (RORγt). It demonstrates significant potential in modulating immune responses, particularly in the context of psoriasis research. This compound serves as a valuable tool for investigating therapeutic strategies targeting autoimmune and inflammatory conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inverse Agonist |
| CAS Number | 2055496-11-0 |
| Applications | RORγt Inverse Agonist |
| Formula | C24H20Cl3F3N2O3 |
| Molecular Weight | 547.78 |
| Synonyms | ABBV-157 |
| SMILES | O=C(CC1CCN(CC1)C(C2=CC=C(C(CN3C=CC4=C3C(Cl)=CC(C(F)(F)F)=C4)=C2Cl)Cl)=O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.