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Publications citing Adooq Products
Celastrol Citations (1)
- Abdin AA, .et al. Modulatory effect of celastrol on Th1/Th2 cytokines profile, TLR2 and CD3+ T-lymphocyte expression in a relapsing-remitting model of multiple sclerosis in rats., Eur J Pharmacol., 2014, 742:102-12 PMID: 25218987
Chemical Information
| Catalog Num | A10192 |
|---|---|
| Actions | No |
| M. Wt | 450.6 |
| Formula | C29H38O4 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 34157-83-0 |
| Synonyms | N/A |
| SMILES | CC1=C(C(=O)C=C2C1=CC=C3[[email protected]]2(CC[[email protected]@]4([[email protected]@]3(CC[[email protected]@]5([[email protected]]4C[[email protected]](CC5)(C)C(=O)O)C)C)C)C)O |
| Chemical Name | 3-hydroxy-9β,13α-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid |
Description |
Celastrol is a triterpenoid antioxidant compound isolated from the Chinese Thunder of God vine (T. wilfordii). In an isolated rat liver assay of lipid peroxidation, celastrol had an IC50 value of 7 µM, equivalent to about 15 times the antioxidant potency of α-tocopherol. |
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Targets |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.19 mL | 110.96 mL | 221.93mL |
| 0.5 mM | 4.44 mL | 22.19 mL | 44.39 mL |
| 1 mM | 2.22 mL | 11.1 mL | 22.19 mL |
| 5 mM | 0.44 mL | 2.22 mL | 4.44 mL |
*The above data is based on the productmolecular weight 450.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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