Celastrol

Catalog No.: A10192

Celastrol

Celastrol Chemical Structure

CAS NO. 34157-83-0

Celastrol is a triterpenoid antioxidant compound isolated from the Chinese Thunder of God vine (T. wilfordii). In an isolated rat liver assay of lipid peroxidation, celastrol had an IC50 value of 7 µM, equivalent to about 15 times the antioxidant potency of α-tocopherol.

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Package Price Qty
10 mg
$50.00
25 mg
$90.00
50 mg
$130.00
100 mg
$175.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Abdin AA, .et al. Modulatory effect of celastrol on Th1/Th2 cytokines profile, TLR2 and CD3+ T-lymphocyte expression in a relapsing-remitting model of multiple sclerosis in rats., Eur J Pharmacol., 2014, 742:102-12 PMID: 25218987

Biological Activity

Celastrol is a triterpenoid antioxidant compound isolated from the Chinese Thunder of God vine (T. wilfordii). In an isolated rat liver assay of lipid peroxidation, celastrol had an IC50 value of 7 µM, equivalent to about 15 times the antioxidant potency of α-tocopherol.

Targets
20S proteasome 20S proteasome
N/A2.5 μM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.19 mL 110.96 mL 221.93 mL
0.5 mM 4.44 mL 22.19 mL 44.39 mL
1 mM 2.22 mL 11.1 mL 22.19 mL
5 mM 0.44 mL 2.22 mL 4.44 mL

*The above data is based on the productmolecular weight 450.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10192
M. Wt 450.6
Formula C29H38O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 34157-83-0
SMILES CC1=C(C(=O)C=C2C1=CC=C3[[email protected]]2(CC[[email protected]@]4([[email protected]@]3(CC[[email protected]@]5([[email protected]]4C[[email protected]](CC5)(C)C(=O)O)C)C)C)C)O

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