Biological Activity
Celastrol is a triterpenoid antioxidant compound isolated from the Chinese Thunder of God vine (T. wilfordii). In an isolated rat liver assay of lipid peroxidation, celastrol had an IC50 value of 7 µM, equivalent to about 15 times the antioxidant potency of α-tocopherol.
Targets
20S proteasome | 20S proteasome | |||
N/A | 2.5 μM |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 22.19 mL | 110.96 mL | 221.93 mL |
0.5 mM | 4.44 mL | 22.19 mL | 44.39 mL |
1 mM | 2.22 mL | 11.1 mL | 22.19 mL |
5 mM | 0.44 mL | 2.22 mL | 4.44 mL |
*The above data is based on the productmolecular weight 450.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A10192 |
---|---|
M. Wt | 450.6 |
Formula | C29H38O4 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 34157-83-0 |
SMILES | CC1=C(C(=O)C=C2C1=CC=C3[[email protected]]2(CC[[email protected]@]4([[email protected]@]3(CC[[email protected]@]5([[email protected]]4C[[email protected]](CC5)(C)C(=O)O)C)C)C)C)O |
Product Tags
Product Questions
Product Questions
No Questions
Keywords:buy Celastrol | Celastrol Supplier | purchase Celastrol | Celastrol cost | Celastrol manufacturer | order Celastrol | Celastrol distributor | buy 34157-83-0| 34157-83-0 Supplier | purchase 34157-83-0 | 34157-83-0 cost | 34157-83-0 manufacturer | order 34157-83-0 | 34157-83-0 distributor