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G-quadruplexe stabilizer
Pyridostatin hydrochloride (RR82 hydrochloride) is a G-quadruplexe stabilizer, with a Kd of 490 nM. -
G-quadruplex DNA Stabilizer
Pyridostatin stabilizes G-quadruplexes (G4s) in cells and elicits a DNA damage response by causing the formation of DNA double strand breaks (DSB).- Payal Gupta, .et al. , ACS Infect Dis, 2025, Mar 14;11(3):784-795 PMID: 40017008
