Catalog No.
Product Name
Application
Product Information
Citations
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Herbicide
2,6-Dichloro-4-nitroaniline acts as a herbicide and uncoupler, targeting oxidative phosphorylation and inhibiting the electron transport chain. This compound has demonstrated the ability to induce biphenyl hydroxylase activity in rat liver models. Additionally, it promotes hepatomegaly, resulting in increased liver weight in rats without affecting overall body weight, making it a valuable reagent for studies involving metabolic and toxicological research. -
Herbicide
4,6,4'-Trihydroxy-3'-methoxyaurone is a potent herbicide that demonstrates inhibitory activity against the growth of various plant seedlings. At concentrations of 100 and 1000 µg/mL, it effectively suppresses the growth of rape root and barnyardgrass, making it a valuable tool in agricultural research. Its unique mechanism offers potential applications in studying herbicidal effects and plant resilience. -
Herbicide
TKL-IN-2 is a selective TKL inhibitor with an IC50 of 0.11 mg/L against SvTKL. This compound demonstrates strong herbicidal activity against key weeds such as Digitaria sanguinalis and Amaranthus retroflexus, while displaying safety profiles for major crops including maize, wheat, soybean, and cotton. TKL-IN-2 is valuable for research focused on developing effective weed control strategies in agricultural settings. -
Proherbicide
Bixlozone is a proherbicide that requires in planta activation to convert into its active phytotoxic form, 5-ketobixlozone. This compound exhibits selective herbicidal activity against annual ryegrass (Lolium rigidum), making it a valuable tool for managing weed populations in Australian cereal and canola crops. Its unique activation mechanism allows for targeted control, contributing to effective weed management in agricultural settings. -
Herbicide
Triclopyr triethylamine is a systemic herbicide that selectively targets broadleaf emergent aquatic weeds. It exhibits significant biological activity by inducing lethargy and delaying metamorphosis in northern red-legged frogs during exposure. This compound is primarily utilized for the management of invasive species, such as Lythrum salicaria, making it valuable in ecological restoration and aquatic weed control research. -
Herbicide
Sodium 4-(4-chloro-O-tolyloxy)butyrate is a phenoxycarboxylic acid herbicide that functions primarily by inhibiting the growth of unwanted plant species. Its mechanism targets specific growth pathways, effectively controlling herbaceous growth in various agricultural settings. This compound is employed in research applications focused on plant physiology and herbicide efficacy studies. -
Herbicide
Pyraflufen is a pyrazolylphenyl herbicide that primarily targets protoporphyrinogen oxidase, an enzyme involved in the biosynthesis of chlorophyll. This selective herbicide effectively controls various broadleaf weeds, making it useful in agricultural applications. Its ability to disrupt photosynthesis contributes to its efficacy in weed management strategies. -
herbicide
Cinmethylin is a systemic herbicide that targets plant fatty acid biosynthesis. It effectively reduces the emergence rate and above-ground biomass of rigid ryegrass and inhibits cell division at root meristems to eliminate weeds. Cinmethylin demonstrates potent activity against paddy field weeds, including Echinochloa crus-galli (L.) var. formosensis and Scirpus juncoides var. ohwianus. This compound is valuable for research in agricultural herbicide development and weed management strategies. -
Herbicide
Chloramben sodium is a selective herbicide that inhibits plant growth by disrupting key physiological processes. It can be effectively degraded through the photo-Fenton reaction at near-neutral pH, demonstrating significant mineralization efficacy, particularly with IrO2-based electrodes under elevated current density. The compound has been shown to generate stable chlorine derivatives in environments containing chlorine, which may reduce its overall removal and mineralization rates. Additionally, Chloramben sodium interacts with various aromatic compounds and organic acids, indicating its complex ecological transformation behaviors. -
Herbicide Safety Agent
Herbicide safener-3 is a selective herbicide safety agent that enhances the efficacy of herbicides while minimizing their harmful effects on crops. By regulating metabolic differences between crops and weeds, this compound promotes the safety of sensitive plants during herbicide application. Herbicide safener-3 is valuable in research focused on optimizing herbicide performance and improving overall crop protection strategies. -
Herbicide
Aminopyralid is a synthetic auxin herbicide that targets auxin-dependent processes in plants. It provides effective foliar and soil residual control of annual and perennial broadleaf weeds, significantly enhancing forage yield in bahiagrass pastures. However, as a soil residue, Aminopyralid can induce phytotoxicity and negatively impact rotated vegetable crops by reducing plant height, flower number, and fruit yield. It is registered for use in pastures, permanent grasslands, and non-cropped areas to manage problematic weed species. -
herbicide
Alloxydim sodium is a cyclohexenone oxime herbicide that primarily targets the biosynthesis of fatty acids in plants. It demonstrates significant cytotoxicity to grassy weeds while being selective for broadleaf crops. This reagent is widely utilized in agricultural research for the management of unwanted grass species in diverse cropping systems. -
Herbicide
Pentoxazone is a protoporphyrinogen IX oxidase (PPO) inhibitor that acts as an effective herbicide. By inhibiting chlorophyll and heme synthesis, it promotes the accumulation and oxidation of protoporphyrinogen IX, leading to the generation of singlet oxygen that damages cell membranes and induces cell death. Pentoxazone demonstrates significant efficacy in suppressing the fresh weight growth of various weed species, while exhibiting limited activity against weedy rice, making it a valuable tool for research into weed management in direct-seeding rice fields. -
Herbicide
IR5790 is a potent herbicide that specifically targets protoporphyrinogen oxidase, exhibiting a strong inhibitory effect with an IC50 of 3 nM. This compound's ability to effectively disrupt the biosynthesis of chlorophyll makes it a valuable tool for agricultural research and development. Its application in studies focused on plant growth regulation and weed management strategies is significant, facilitating advancements in herbicide efficacy and crop protection. -
herbicide
Triazole sulcotrione is a triazole herbicide that primarily targets the suppression of weeds in agricultural settings. It exhibits effective herbicidal activity, making it particularly useful in corn cultivation for the management of unwanted flora. This compound is employed in research applications focused on weed biology, herbicide resistance, and crop protection strategies. -
Herbicide
2,3,5-Trichloro-4-pyridinol is an effective herbicide known for its selective action in controlling unwanted vegetation in rice cultivation. It is particularly suited for use in direct-seeded and flooded rice systems, providing researchers with a valuable tool for studying plant competition and herbicide efficacy. Its biological activity facilitates investigations into herbicide modes of action and resistance mechanisms in agricultural settings. -
Endogenous Metabolite
2,4-Dihydroxybutanoic acid is an endogenous metabolite associated with metabolic pathways related to succinic semialdehyde dehydrogenase deficiency. This compound is typically undetectable in normal human urine but is found in elevated levels in affected individuals. It serves as a valuable biomarker for metabolic disorders and can aid in the study of neurological conditions linked to enzyme deficiencies. -
Endogenous Metabolite
hLTA4H/hLTA4S-IN-1 is a dual inhibitor targeting human leukotriene hydrolase (hLTA4H) and human leukotriene C4 synthase (hLTC4S). This compound effectively disrupts the leukotriene biosynthesis pathway, making it valuable for studying inflammatory responses at the cellular level. hLTA4H/hLTA4S-IN-1 serves as a useful tool for research focused on leukotriene-related diseases and inflammatory conditions. -
Endogenous Metabolite
1-Stearo-3-linolein is a diacylglycerol featuring stearic acid at the sn-1 position and linoleic acid at the sn-3 position. This compound serves as an endogenous metabolite with implications in lipid metabolism and signaling pathways. It is utilized in research to study the roles of diacylglycerols in cellular processes and their effects on various biochemical pathways. -
Endogenous Metabolite
14β,16β-Dihydroxy-3β-(β-D-glucopyranosyloxy)-5α-bufa-20,22-dienolide is an endogenous metabolite characterized by its butadiene lactone structure. This compound exhibits significant biological activity in various metabolic pathways, making it a valuable tool for research in life sciences. Its potential applications include studying metabolic processes and exploring molecular interactions in biological systems. -
Endogenous Metabolite
AP219 is a control compound featuring a mitochondria-targeting triphenylphosphonium scaffold, specifically designed for research applications involving endogenous metabolites. While AP219 does not release hydrogen sulfide (H2S), it serves as a valuable tool for studying the effects of H2S in mitochondrial processes when used alongside H2S-releasing compounds like AP39. This compound can aid in elucidating the role of mitochondrial H2S in cellular biology and its potential implications in various disease models. -
Endogenous Metabolite
KRP-109 is a potent inhibitor of neutrophil elastase (NE), demonstrating significant activity in mitigating lung inflammation. In mouse models, KRP-109 has been shown to enhance survival rates and decrease neutrophil accumulation within the alveolar walls. This compound effectively reduces cell and neutrophil counts in bronchoalveolar lavage fluid, as well as lowers levels of pro-inflammatory cytokines, including interleukin 1β and macrophage inflammatory protein 2. KRP-109 is valuable for research focused on severe pneumonia and associated inflammatory conditions. -
Endogenous Metabolite
1,2-Dinonanoyl-sn-glycero-3-phosphocholine is an endogenous metabolite that serves as a specific phosphatidylcholine, influencing membrane dynamics through its unique fatty acyl configurations. This phospholipid plays a crucial role in membrane composition and is essential for the generation of eicosanoids. Its structure, with fatty acids linked to glycerol at the sn-1 and sn-2 positions via ester bonds, positions it as an important reagent for studying lipid signaling and membrane biology. -
Endogenous Metabolite
3-(Stearoyloxy)propane-1,2-diyl dioleate is a triacylglycerol derivative characterized by oleic acid at the sn-1 and sn-2 positions, while stearic acid occupies the sn-3 position. This endogenous metabolite is found in various plant oils, including sunflower, corn, and soybean oils, as well as ostrich oil. Its unique structure and fatty acid composition make it valuable for studies in lipid metabolism, cellular signaling, and the exploration of dietary fats in nutritional research. -
Endogenous Metabolite
Rofleponide epimer is an endogenous metabolite that targets glucocorticoid receptors, exhibiting significant anti-inflammatory activity. It demonstrates high selectivity for lung tissues and effectively binds to the rat thymic glucocorticoid receptor, reinforcing its pharmacological efficacy. Additionally, Rofleponide epimer has a biotransformation rate that is ten times greater than that of similar compounds, highlighting its potential for therapeutic applications in managing inflammatory diseases affecting mucosal surfaces. -
Endogenous Metabolite
Pitstop 1 is a small molecule inhibitor that targets the endocytic pathway. It effectively disrupts the interaction between chaperones and the Krasin terminal domain, leading to altered Krasin functionality. This compound demonstrates potent biological activity by inhibiting Krasin-mediated signaling and is valuable in research applications focused on viral entry and pathogen interactions with host cells. -
Endogenous Metabolite
MK-6186 is a novel non-nucleoside reverse transcriptase inhibitor that demonstrates sub-nanomolar activity against wild-type viruses and common NNRTI-resistant RT mutants, including K103N and Y181C. This compound exhibits significant antiviral efficacy, particularly against K103N and Y181C mutant strains. When evaluated against 12 common NNRTI-associated mutant viruses, MK-6186 shows minimal resistance, with most viral strains demonstrating fold change values below 10. In clinical virus isolates harboring NNRTI-resistant mutations, a majority exhibit significantly reduced resistance to MK-6186 compared to other treatments. This positions MK-6186 as a promising candidate for research focused on combating NNRTI-resistant HIV strains. -
Endogenous Metabolite
D-myo-Inositol-1,4,5,6-tetraphosphate (D-Ins(1,4,5,6)P4) functions primarily as an endogenous metabolite involved in cellular signaling pathways. This compound exhibits a strong inhibitory effect on calcium-activated chloride channels, effectively operating at concentrations of 8-10 μM. It is commonly utilized in research applications focused on signal transduction and ion channel regulation. -
Endogenous Metabolite
1-Myristoyl-2-Linoleoyl-3-Oleoyl-rac-glycerol is a triacylglycerol composed of myristic acid, linoleic acid, and oleic acid at the sn-1, sn-2, and sn-3 positions, respectively. This compound is recognized as an endogenous metabolite and is naturally occurring in mature human milk, infant formula fats, and butterfat. It plays a significant role in lipid metabolism and can be utilized in research focused on nutrition, fat digestion, and developmental studies. -
Endogenous Metabolite
2,6,6-Trimethylbicyclo[3.1.1]heptan-3-ol is an endogenous metabolite primarily isolated from Chrysanthemum indicum L. This compound exhibits potential biological activity relevant to various biochemical pathways. It serves as a valuable tool in research focused on the metabolic profiles of plant-derived substances and their implications in pharmacological studies. -
Endogenous Metabolite
(S)-Pomalidomide is an angiogenesis-inhibiting compound that targets endogenous metabolites to exhibit significant growth-inhibitory effects on B-cell tumors. It has demonstrated the capacity to induce complete tumor regression in Burkitt lymphoma cells, making it a valuable tool in cancer research. Additionally, (S)-Pomalidomide functions as an immunomodulator, with potential applications in the treatment of hematological malignancies. -
Leukotrienes
14,15-Leukotriene C4 is a leukotriene compound generated from the enzymatic metabolism of arachidonic acid. This molecule plays a pivotal role in promoting inflammatory responses by enhancing vascular permeability, resulting in the extravasation of fluid and white blood cells into surrounding tissues. Due to its biological activity, 14,15-Leukotriene C4 is valuable for research applications related to asthma and various inflammatory disorders. -
Endogenous Metabolite
12-OxoETE is an endogenous metabolite that functions primarily through leukotriene B4 receptors, eliciting a rapid, dose-dependent increase in cytoplasmic free calcium levels. This compound is valuable in research focusing on calcium signaling pathways and the roles of eicosanoids in cellular responses. Its effects on calcium mobilization make it a useful tool for studying inflammatory processes and leukocyte activation. -
Endogenous Metabolite
8-iso-13,14-dihydro-15-keto Prostaglandin F2α is an oxidative metabolite of 8-iso-prostaglandin F2α, functioning as an endogenous metabolite. This compound plays a significant role in the study of oxidative stress-related diseases by providing insights into the biological effects of oxidative damage on cellular pathways. Its applications extend to research on various pathological conditions influenced by oxidative stress, helping to deepen the understanding of disease mechanisms and potential therapeutic interventions. -
Fungal Metabolite
tert-Pentylbenzene is a volatile aromatic hydrocarbon identified as a fungal metabolite. It can be isolated from the saprophytic fungus Memnoniella sp. This compound is of interest in research applications focused on fungal biochemistry and metabolic profiling, contributing insights into fungal metabolite diversity and ecological roles. -
Endogenous Metabolite
Hepaxanthin, also known as 5,6-Monoepoxy vitamin A or 5,6-Epoxyretinol, is an endogenous metabolite derived from 5,6-monoepoxyvitamin A aldehyde. While it is considered an inactive carotenoid, its accumulation in the liver suggests potential roles in metabolic pathways related to vitamin A metabolism. This compound can be utilized in research studying vitamin A derivatives and their impact on liver function. -
Endogenous Metabolite Inhibitor
NADH-IN-2 is a potent inhibitor of Type II NADH dehydrogenase, an enzyme involved in the electron transport chain and cellular respiration. By selectively targeting this enzyme, NADH-IN-2 can modulate metabolic processes and influence energy production in cells. This compound is useful in research applications investigating bioenergetics, mitochondrial function, and metabolic disorders. -
Endogenous Metabolite
1-Stearoyl-2-adrenoyl-sn-glycero-3-PE is a phospholipid characterized by the presence of stearic acid and adrenic acid at the sn-1 and sn-2 positions, respectively. This endogenous metabolite has been shown to demonstrate an inverse correlation with age in mitochondria extracted from human post-mortem hippocampus, suggesting its potential role in age-related mitochondrial function. It serves as a valuable tool for research into lipid metabolism and neuronal health. -
Endogenous Metabolite
Lantanose A is an oligosaccharide derived from the root of Lantana camara, serving as an endogenous metabolite. It exhibits significant biological activity and is of interest in various research applications, particularly in the study of plant metabolism and interactions with biological systems. Researchers may explore its potential benefits in understanding metabolic pathways and physiological responses in different organisms. -
Fungal Metabolite
Avellanin B is a fungal metabolite known for its pressor effects. It exhibits significant bioactivity that may modulate vascular resistance and blood pressure. This compound can be utilized in research focused on cardiovascular dysfunction and the physiological impacts of fungal metabolites. -
Endogenous Metabolite
Laidlomycin propionate is an endogenous metabolite that enhances weight gain and feed conversion efficiency in livestock. It is primarily used as a feed additive in cattle farming, demonstrating significant improvements in daily weight gain, feed intake, and carcass weight. Extensive research has highlighted its potential to reduce production costs and increase profitability within the cattle industry, although findings may vary across different studies in North America. -
Endogenous Metabolite
Diethylumbelliferyl phosphate (DEUP) acts as a selective and potent inhibitor of cholesterol esterase. This compound effectively disrupts steroidogenesis by inhibiting the transport of cholesterol into the mitochondria of steroidogenic cells, with an IC50 of 11.6 μM. DEUP is valuable in research applications focused on cholesterol metabolism and steroid hormone synthesis. -
Endogenous Metabolite
Aspergillomarasmine A is a natural aminopolycarboxylic acid that functions as an inhibitor of class B metallo-β-lactamases (MBLs). It specifically inactivates these enzymes by chelating the essential Zn2+ cofactor, effectively promoting the degradation of zinc-deficient NDM-1 and enhancing the efficacy of β-lactam antibiotics. This compound serves as a selective Zn2+ scavenger, demonstrating broad potential for research applications aimed at understanding and overcoming β-lactam resistance in bacterial pathogens. -
Endogenous Metabolite
22:0 PC (1,2-Didocosanoyl-sn-glycero-3-phosphocholine) is an endogenous metabolite primarily acting as a lung surfactant. As an amphipathic phosphatidylcholine, it is mainly localized in the outer leaflets of biological membrane bilayers. This compound is crucial for maintaining alveolar stability and surface tension, making it valuable for research applications in pulmonary biology, membrane dynamics, and lipid metabolism studies. -
Endogenous Metabolite
LAPAO (Laurylamidopropyldimethylamine oxide) is an amphoteric surfactant known for its excellent biocompatibility and surface-active properties. It exhibits significant detergent and foam-enhancing capabilities, making it suitable for applications in personal care and household cleaning products. LAPAO maintains stability across a range of pH values and effectively removes dirt and grease, while also providing conditioning benefits that enhance the performance of skin and hair care formulations. -
Endogenous Metabolite
Hemi-Oxanthromicin A is a polyketide derived from the bacterium Streptomyces. This compound acts as an endogenous metabolite, exhibiting notable antibacterial activity. It is primarily utilized in research focused on microbial secondary metabolites and their potential therapeutic applications. -
Insect Pheromone
(Z)-10-Hexadecenal is an insect pheromone primarily involved in mediating attraction between mating partners. This compound has been identified as a fruit-type female pheromone derived from the abdominal tip extracts of female Dichocrocis punctiferalis. Its unique properties make it valuable for use in ecological studies and pest management research, facilitating investigations into insect behavior and communication. -
Endogenous Metabolite
(Z)-9-Heptadecenoic Acid is an endogenous metabolite classified as a monounsaturated fatty acid. This compound serves as a significant component of ruminant fat and milk, where its concentrations have been observed to negatively correlate with methane production in cattle on high-lipid diets. Research applications include studies on lipid metabolism, ruminant nutrition, and the mitigation of greenhouse gas emissions in livestock. -
Pheromone
Nonacosadiene is a natural pheromone derived from Drosophila melanogaster, functioning primarily as a chemical signal for communication among individuals. This compound plays a crucial role in mating behavior and social interaction within the species. Its unique properties make it valuable for research in behavioral ecology, chemical communication, and the study of pheromone mechanisms. -
Endogenous Metabolite
Propyl nicotinate, also known as nicotinic acid propyl ester, is an endogenous metabolite that serves as the propyl ester of niacin. It plays a crucial role in the biosynthesis of coenzymes NAD and NADP, which are essential for various metabolic processes. Propyl nicotinate is utilized in research focusing on metabolic regulation and coenzyme activity, contributing to the understanding of cellular respiration and energy metabolism.
