Fig. 1 · Structure
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Centanafadine hydrochloride
Serotonin Transporter Inhibitor
Centanafadine hydrochloride is a serotonin transporter inhibitor that also inhibits norepinephrine (NE) and dopamine (DA) transporters. It demonstrates effective activity with IC50 values of 6 nM for the NE transporter, 38 nM for the DA transporter, and 83 nM for the serotonin transporter. This compound is useful in research focused on mood disorders, attention-deficit/hyperactivity disorder (ADHD), and other neuropsychiatric conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 923981-14-0 |
| Applications | Serotonin Transporter Inhibitor |
| Formula | C15H16ClN |
| Molecular Weight | 245.75 |
| Synonyms | EB-1020 hydrochloride |
| SMILES | [C@@H]12[C@@](CNC2)(C3=CC(C=CC=C4)=C4C=C3)C1.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.