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Centanamycin

DNA-binding agent

Centanamycin is a novel DNA-binding agent that exhibits significant cytotoxic activity, demonstrated by an average GI50 of 34 nM in the NCI-60 cancer cell line panel. Its mechanism targets DNA, making it a valuable compound for research in cancer biology and therapeutic development. Centanamycin can be utilized to explore DNA-interactive processes and the underlying mechanisms of action in cellular responses to DNA damage.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	413577-16-9
Applications	DNA-binding agent
Formula	C₂₄H₂₄ClN₃O₄
Molecular Weight	453.92
Synonyms	ML-970; AS-I-145; NSC 716970
SMILES	O=C(C1=CC2=C(N1)C(OC)=C(OC)C(OC)=C2)NC3=C(CCCl)C4=C(C=CC=C4)C(N)=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.