Fig. 1 · Structure
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Cephaeline dihydrochloride
Cytochrome P450 Inhibitor
Cephaeline dihydrochloride is a selective inhibitor of cytochrome P450 2D6 (CYP2D6), exhibiting an IC50 of 121 μM. This compound is utilized in research focusing on drug metabolism and pharmacogenomics, providing insights into CYP2D6-mediated drug interactions and variations in drug efficacy. Its specificity for CYP2D6 makes it a valuable tool for studies investigating the role of this enzyme in pharmacological responses.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 5853-29-2 |
| Applications | Cytochrome P450 Inhibitor |
| Formula | C28H40Cl2N2O4 |
| Molecular Weight | 539.53 |
| Synonyms | (-)-Cephaeline dihydrochloride; NSC 32944 |
| SMILES | Cl[H].CC[C@@H](CN1CC2)[C@H](C[C@@]1([H])C3=C2C=C(OC)C(OC)=C3)C[C@]4([H])C5=CC(OC)=C(O)C=C5CCN4.Cl[H] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.