ZIKV And EBOV Inhibitor, Histone H3 Acetylation Inductor, Ferroptosis Inductor
Cephaeline is a phenolic alkaloid derived from the roots of Cephaelis ipecacuanha, functioning as a potent inhibitor of Zika virus (ZIKV) and Ebola virus (EBOV) infections. It induces histone H3 acetylation, playing a role in epigenetic regulation, and has been shown to induce ferroptosis in mucoepidermoid carcinoma cancer stem cells by inhibiting NRF2. This makes Cephaeline a valuable reagent for researchers studying antiviral mechanisms and ferroptosis in cancer therapy.
Cephaeline is a phenolic alkaloid derived from the roots of Cephaelis ipecacuanha, functioning as a potent inhibitor of Zika virus (ZIKV) and Ebola virus (EBOV) infections. It induces histone H3 acetylation, playing a role in epigenetic regulation, and has been shown to induce ferroptosis in mucoepidermoid carcinoma cancer stem cells by inhibiting NRF2. This makes Cephaeline a valuable reagent for researchers studying antiviral mechanisms and ferroptosis in cancer therapy.
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