Cephaeline

Catalog No.: A27060
ZIKV And EBOV Inhibitor, Histone H3 Acetylation Inductor, Ferroptosis Inductor
Cephaeline is a phenolic alkaloid derived from the roots of Cephaelis ipecacuanha, functioning as a potent inhibitor of Zika virus (ZIKV) and Ebola virus (EBOV) infections. It induces histone H3 acetylation, playing a role in epigenetic regulation, and has been shown to induce ferroptosis in mucoepidermoid carcinoma cancer stem cells by inhibiting NRF2. This makes Cephaeline a valuable reagent for researchers studying antiviral mechanisms and ferroptosis in cancer therapy.
Grouped product items
Size Price Stock Qty
1mg
$100.00
In stock
5mg
$215.00
In stock
10mg
$345.00
In stock
25mg
$565.00
In stock
50mg
$770.00
In stock
100mg
$1,010.00
In stock
200mg
$1,310.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCephaeline is a phenolic alkaloid derived from the roots of Cephaelis ipecacuanha, functioning as a potent inhibitor of Zika virus (ZIKV) and Ebola virus (EBOV) infections. It induces histone H3 acetylation, playing a role in epigenetic regulation, and has been shown to induce ferroptosis in mucoepidermoid carcinoma cancer stem cells by inhibiting NRF2. This makes Cephaeline a valuable reagent for researchers studying antiviral mechanisms and ferroptosis in cancer therapy.
Product Information
Catalog NumA27060
FormulaC28H38N2O4
Molecular Weight466.61
CAS Number483-17-0
SMILESOC1=CC2=C([C@@H](C[C@@H]3[C@@H](CC)CN4CCC5=CC(OC)=C(OC)C=C5[C@]4([H])C3)NCC2)C=C1OC
Synonyms(-)-Cephaeline; NSC 32944 free base
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