Fig. 1 · Structure

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Cetirizine Impurity D

H1 Antagonist

Cetirizine Impurity D is an impurity of the well-known antihistamine Cetirizine, acting primarily as a histamine H1-receptor antagonist. This compound demonstrates significant antiallergic properties, effectively inhibiting eosinophil chemotaxis during allergic responses. It serves as a useful research tool for studying the pharmacological effects and safety profiles of antihistamines in various biological systems.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 346451-15-8
Applications H1 Antagonist
Formula C30H28Cl2N2
Molecular Weight 487.46
SMILES
ClC1=CC=C(C(N2CCN(C(C3=CC=C(Cl)C=C3)C4=CC=CC=C4)CC2)C5=CC=CC=C5)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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