Signaling Pathway
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| Discription | CGI1746 is a small-molecule Btk inhibitor chemotype with a new binding mode that stabilizes an inactive nonphosphorylated enzyme conformation. | ||
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| Targets |
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| Catalog Num | A11348 |
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| Formula | C34H37N5O4 |
| Molecular Weight | 579.7 |
| CAS Number | 910232-84-7 |
| SMILES | CC1=C(C=CC=C1NC(=O)C2=CC=C(C=C2)C(C)(C)C)C3=CN(C(=O)C(=N3)NC4=CC=C(C=C4)C(=O)N5CCOCC5)C |
| Synonyms | CGI 1746, CGI-1746 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 91 mg/mL (156.98 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 30 mg/mL (51.75 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.25 mL | 86.25 mL | 172.5 mL |
| 0.5 mM | 3.45 mL | 17.25 mL | 34.5 mL |
| 1 mM | 1.73 mL | 8.63 mL | 17.25 mL |
| 5 mM | 0.35 mL | 1.73 mL | 3.45 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
