Fig. 1 · Structure

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CH2COOH-PEG12-CH2COOH

PROTAC Linkers

CH2COOH-PEG12-CH2COOH is a PEG-based PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the development of targeted protein degradation strategies by linking E3 ligases to protein targets, enhancing cellular selectivity and efficacy. It is suitable for use in various research applications focused on elucidating protein function and investigating therapeutic interventions in disease models.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2669737-17-9
Applications PROTAC Linkers
Formula C28H54O17
Molecular Weight 662.72
SMILES
OC(COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC(O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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