Fig. 1 · Structure

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CH2COOH-PEG9-CH2COOH

PROTAC Linkers

CH2COOH-PEG9-CH2COOH is a PEG-based linker specifically designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the conjugation of target proteins to E3 ligases, enabling targeted protein degradation. Its unique structure supports improved solubility and flexibility, enhancing the efficacy of PROTAC strategies in chemical biology research.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2250056-46-1
Applications PROTAC Linkers
Formula C22H42O14
Molecular Weight 530.56
SMILES
O=C(O)COCCOCCOCCOCCOCCOCCOCCOCCOCCOCC(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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