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Chaetoglobosin A

Catalog No.: A30818
Apoptosis Inducer
Chaetoglobosin A is a potent apoptosis inducer derived from the extract of Penicillium aquamarinium and belongs to the cytochalasan family. It selectively targets filamentous actin in chronic lymphocytic leukemia (CLL) cells, leading to cell-cycle arrest and inhibition of membrane ruffling and cell migration. This compound is valuable for research in apoptosis mechanisms and cancer therapeutics.
Chaetoglobosin A 50335-03-0 Apoptosis Inducer
Grouped product items
Size Price Stock Qty
1mg
$135.00
In stock
5mg
$1,395.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionChaetoglobosin A is a potent apoptosis inducer derived from the extract of Penicillium aquamarinium and belongs to the cytochalasan family. It selectively targets filamentous actin in chronic lymphocytic leukemia (CLL) cells, leading to cell-cycle arrest and inhibition of membrane ruffling and cell migration. This compound is valuable for research in apoptosis mechanisms and cancer therapeutics.
Product Information
Catalog NumA30818
FormulaC32H36N2O5
Molecular Weight528.64
CAS Number50335-03-0
SMILESO=C(/C=C/C1=O)[C@H](O)/C(C)=C/[C@@H](C)C/C=C/[C@]2([H])[C@]31C(N[C@@H](CC4=CNC5=C4C=CC=C5)[C@]3([H])[C@H](C)[C@]6(C)[C@@]2([H])O6)=O
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Apoptosis > Apoptosis Inducers