Fig. 1 · Structure
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Chaparrinone
Antimalarial Agent
Chaparrinone is a quassinoid derived from the root of Eurycoma harmandiana, exhibiting potent antimalarial activity. It demonstrates cytotoxic effects against Plasmodium falciparum and P-388 cells, with IC50 values of 0.037 μg/mL and 0.34 μg/mL, respectively. This compound is valuable for research applications focused on malaria treatment and cancer cell viability studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 22611-34-3 |
| Applications | Antimalarial Agent |
| Formula | C20H26O7 |
| Molecular Weight | 378.42 |
| SMILES | C[C@@]12[C@]3([H])[C@@]45[C@@](OC(C[C@@]4([H])[C@H]([C@H]([C@@]3(OC5)O)O)C)=O)([H])C[C@@]1([H])C(C)=CC([C@H]2O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.