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CHF5074 is a novel γ-secretase modulator, reduces Aβ42 and Aβ40 secretion, with an IC50 of 3.6 and 18.4 uM, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.75 mL | 153.77 mL | 307.54 mL |
| 0.5 mM | 6.15 mL | 30.75 mL | 61.51 mL |
| 1 mM | 3.08 mL | 15.38 mL | 30.75 mL |
| 5 mM | 0.62 mL | 3.08 mL | 6.15 mL |
*The above data is based on the productmolecular weight 325.16. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A16214 |
|---|---|
| Actions | Modulator |
| M. Wt | 325.16 |
| Formula | C16H11Cl2FO2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 749269-83-8 |
| Synonyms | CSP-1103, CHF-5074 |
| SMILES | O=C(C1(C2=CC=C(C3=CC=C(Cl)C(Cl)=C3)C(F)=C2)CC1)O |
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