CHF5074

Catalog No.: A16214

γ-Secretase modulator

CHF5074

CHF5074 Chemical Structure

CAS NO. 749269-83-8

CHF5074 is a novel γ-secretase modulator, reduces Aβ42 and Aβ40 secretion, with an IC50 of 3.6 and 18.4 uM, respectively.

Availability: In stock

Package Price Qty
5 mg
$100.00
10 mg
$150.00
50 mg
$500.00
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Biological Activity

CHF5074 is a novel γ-secretase modulator, reduces Aβ42 and Aβ40 secretion, with an IC50 of 3.6 and 18.4 uM, respectively.
In vitro DMSO 51 mg/mL (156.84 mM)
Water Insoluble
Ethanol 8 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.75 mL 153.77 mL 307.54 mL
0.5 mM 6.15 mL 30.75 mL 61.51 mL
1 mM 3.08 mL 15.38 mL 30.75 mL
5 mM 0.62 mL 3.08 mL 6.15 mL

*The above data is based on the productmolecular weight 325.16. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16214
Actions Modulator
CAS No. 749269-83-8
Formula C16H11Cl2FO2
M. Wt 325.16
Purity >98%
Synonyms CSP-1103, CHF-5074
SMILES O=C(C1(C2=CC=C(C3=CC=C(Cl)C(Cl)=C3)C(F)=C2)CC1)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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