CHF5074

Catalog No.: A16214

γ-Secretase modulator

CHF5074

CHF5074 Chemical Structure

CAS NO. 749269-83-8

CHF5074 is a novel γ-secretase modulator, reduces Aβ42 and Aβ40 secretion, with an IC50 of 3.6 and 18.4 uM, respectively.

Availability: In stock

Package Price Qty
5 mg
$320.00
10 mg
$480.00
50 mg
$1,400.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

CHF5074 is a novel γ-secretase modulator, reduces Aβ42 and Aβ40 secretion, with an IC50 of 3.6 and 18.4 uM, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.75 mL 153.77 mL 307.54 mL
0.5 mM 6.15 mL 30.75 mL 61.51 mL
1 mM 3.08 mL 15.38 mL 30.75 mL
5 mM 0.62 mL 3.08 mL 6.15 mL

*The above data is based on the productmolecular weight 325.16. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A16214
Actions Modulator
M. Wt 325.16
Formula C16H11Cl2FO2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 749269-83-8
Synonyms CSP-1103, CHF-5074
SMILES O=C(C1(C2=CC=C(C3=CC=C(Cl)C(Cl)=C3)C(F)=C2)CC1)O

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