Fig. 1 · Structure
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CHF5407
Muscarinic M3 Receptor Antagonist
CHF5407 is a selective, competitive antagonist of the muscarinic M3 receptor, exhibiting subnanomolar affinities for human muscarinic receptors M1, M2, and M3. This compound demonstrates prolonged antibronchospastic activity, making it a valuable tool for research into bronchial hyperreactivity and related respiratory conditions. CHF5407 is suitable for studies investigating the role of muscarinic receptors in various biological processes and potential therapeutic applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1004312-94-0 |
| Applications | Muscarinic M3 Receptor Antagonist |
| Formula | C27H25BrF4N2O3S |
| Molecular Weight | 613.46 |
| SMILES | O=C(C1=CC=CS1)C[N+]23C[C@@H](C(CC3)CC2)OC(N(C4=CC(F)=CC=C4)CC5=CC(F)=C(F)C(F)=C5)=O.[Br-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.