CHI3L1-IN-2

Catalog No.: A75070
CHI3L1:HSIII Inhibitor
CHI3L1-IN-2 is a selective inhibitor of CHI3L1 (Chitinase-3-Like Protein 1) that targets its interaction with heparan sulfate (CHI3L1:HSIII), exhibiting an IC50 of 26 nM. CHI3L1 is a glycoprotein linked to various pathological conditions including inflammation, fibrosis, and cancer. This compound serves as a valuable tool for researchers investigating the role of CHI3L1 in disease processes and therapeutic applications.
Grouped product items
Size Price Stock Qty
5mg
$370.00
In stock
10mg
$600.00
In stock
25mg
$1,260.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCHI3L1-IN-2 is a selective inhibitor of CHI3L1 (Chitinase-3-Like Protein 1) that targets its interaction with heparan sulfate (CHI3L1:HSIII), exhibiting an IC50 of 26 nM. CHI3L1 is a glycoprotein linked to various pathological conditions including inflammation, fibrosis, and cancer. This compound serves as a valuable tool for researchers investigating the role of CHI3L1 in disease processes and therapeutic applications.
Product Information
Catalog NumA75070
FormulaC26H37ClN4
Molecular Weight441.05
CAS Number2982257-63-4
SMILESCC(C)C[C@H](N(C1)C)CN(C2CCN(C3=CC=CC=N3)CC2)[C@H]1CC4=CC=C(C=C4)Cl
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