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CHI3L1-IN-6

CHI3L1 Inhibitor

CHI3L1-IN-6 is a selective inhibitor of CHI3L1, demonstrating a Kd of 19.11 µM for human CHI3L1. By disrupting the interaction between CHI3L1 and Galectin-3, this compound effectively reduces STAT3 signaling. CHI3L1-IN-6 has shown promise in exhibiting anti-cancer activity, particularly in the treatment of glioblastoma, making it a valuable tool for cancer research and therapeutic development.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1914772-75-0
Applications	CHI3L1 Inhibitor
Formula	C₁₄H₁₆ClN₃O
Molecular Weight	277.75
SMILES	ClC1=CC2=C(C=C1)CC(NCCC3=NOC(C)=N3)C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.