Fig. 1 · Structure
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Chinifur
Trypanothione Reductase Inhibitor
Chinifur, a nitrofuran derivative, serves as a selective inhibitor of trypanothione reductase, exhibiting a Ki value of 4.5 μM. This compound functions as a radical-generating substrate for the enzyme, facilitating further studies on oxidative stress pathways. Its inhibition of trypanothione reductase makes Chinifur a valuable tool in investigating mechanisms of trypanosomiasis and related cellular processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 70762-66-2 |
| Applications | Trypanothione Reductase Inhibitor |
| Formula | C25H30N4O4 |
| Molecular Weight | 450.53 |
| Synonyms | Quinifuryl |
| SMILES | O=C(C1=C2C=CC=CC2=NC(/C=C/C3=CC=C([N+]([O-])=O)O3)=C1)NC(CCCN(CC)CC)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.