Fig. 1 · Structure
Documents & Downloads
Chlorambucyl-proline
Cat. No.
A73208
CAS
81050-71-7
Endogenous Metabolite
Chlorambucyl-proline is an amino acid derivative exhibiting inhibitory activity against bovine pulmonary vasoconstrictor enzyme. This compound functions as an irreversible inhibitor by forming ester bonds with the enzyme's aspartic or glutamic acid residues, leading to permanent enzyme inactivation. The rate of inactivation by chlorambucyl-proline is influenced by pH, with increased activity observed in the 5-8 range, making it a valuable tool for studying enzymatic regulation and function in physiological pH environments.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 81050-71-7 |
| Applications | Endogenous Metabolite |
| Formula | C19H26Cl2N2O3 |
| Molecular Weight | 401.33 |
| SMILES | O=C(O)[C@H]1N(C(CCCC2=CC=C(N(CCCl)CCCl)C=C2)=O)CCC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.