Chlorpyrifos-d10 is a deuterium-labeled variant of Chlorpyrifos, an organophosphate insecticide known for its action as a phosphorothionate. Its active metabolite, Chlorpyrifos oxon, functions as a potent inhibitor of acetylcholinesterase (AChE), thereby disrupting neurological function in a range of organisms, including insects and mammals. This stable isotope is valuable for studying metabolic pathways, neurotoxic effects, and enzyme interactions, particularly in the context of susceptibility to neurotoxicity modulated by plasma enzyme paraoxonase 1 (PON1).
Chlorpyrifos-d10 is a deuterium-labeled variant of Chlorpyrifos, an organophosphate insecticide known for its action as a phosphorothionate. Its active metabolite, Chlorpyrifos oxon, functions as a potent inhibitor of acetylcholinesterase (AChE), thereby disrupting neurological function in a range of organisms, including insects and mammals. This stable isotope is valuable for studying metabolic pathways, neurotoxic effects, and enzyme interactions, particularly in the context of susceptibility to neurotoxicity modulated by plasma enzyme paraoxonase 1 (PON1).
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