CHMFL-ABL-039

Catalog No.: A13182

BCR-ABL inhibitor

CHMFL-ABL-039

CHMFL-ABL-039 Chemical Structure

CAS NO. 2304344-56-5

CHMFL-ABL-039 is a type II native ABL kinase and drug-resistant V299L mutant BCR-ABL inhibitor with the IC50s of 7.9 nM and 27.9 nM, respectively. CHMFL-ABL-039 is used in the research of chronic myeloid leukemia.

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

CHMFL-ABL-039 is a type II native ABL kinase and drug-resistant V299L mutant BCR-ABL inhibitor with the IC50s of 7.9 nM and 27.9 nM, respectively. CHMFL-ABL-039 is used in the research of chronic myeloid leukemia.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.82 mL 84.09 mL 168.17 mL
0.5 mM 3.36 mL 16.82 mL 33.63 mL
1 mM 1.68 mL 8.41 mL 16.82 mL
5 mM 0.34 mL 1.68 mL 3.36 mL

*The above data is based on the productmolecular weight 594.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13182
Actions Inhibitor
M. Wt 594.63
Formula C31H33F3N6O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 2304344-56-5
SMILES O=C(NC1=CN=C(NC(C2CC2)=O)C=C1)CC3=CC=C(NC(C4=CC=C(CN5CCN(C)CC5)C(C(F)(F)F)=C4)=O)C=C3

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