Fig. 1 · Structure
Documents & Downloads
Chol-N3
Chol Probe
Chol-N3 is a bioorthogonal chol probe that targets cholesterol molecules in cellular membranes. Its primary mechanism involves click chemistry, facilitating the copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions. Chol-N3 enables the direct visualization of nanoscale lipid heterogeneity using super-resolution fluorescence microscopy (SRM), making it a valuable tool for investigating cellular lipid dynamics and membrane organization in live cells. This reagent is essential for research applications focused on lipid biology, membrane structure, and cellular signaling.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2106868-12-4 |
| Applications | Chol Probe |
| Formula | C24H39N3O |
| Molecular Weight | 385.59 |
| SMILES | C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCN=[N+]=[N-])([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C[C@H](CC4)O)=CC3)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.