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Cholecystokinin (27-32)-amide

Catalog No.: A59689
CCK Receptor Antagonist
Cholecystokinin (27-32)-amide is a potent antagonist of the cholecystokinin (CCK) receptor, primarily interfering with CCK-mediated signaling pathways. This compound exhibits significant biological activity in regulating digestive processes and satiety. It is widely utilized in research applications focused on gastrointestinal function, neuropeptide signaling, and potential therapeutic interventions for related disorders.
Cholecystokinin (27-32)-amide 86367-90-0 CCK Receptor Antagonist
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCholecystokinin (27-32)-amide is a potent antagonist of the cholecystokinin (CCK) receptor, primarily interfering with CCK-mediated signaling pathways. This compound exhibits significant biological activity in regulating digestive processes and satiety. It is widely utilized in research applications focused on gastrointestinal function, neuropeptide signaling, and potential therapeutic interventions for related disorders.
Product Information
Catalog NumA59689
FormulaC36H48N8O12S3
Molecular Weight881.01
CAS Number86367-90-0
Sequence{Tyr(SO3H)}-Met-Gly-Trp-Met-Asp-NH2
Sequence shortening{Tyr(SO3H)}-MGWMD-NH2
SMILESC([C@@H](C(N[C@H](C(N[C@@H](CC(O)=O)C(N)=O)=O)CCSC)=O)NC(CNC([C@@H](NC([C@H](CC1=CC=C(OS(=O)(=O)O)C=C1)N)=O)CCSC)=O)=O)C=2C=3C(NC2)=CC=CC3
SynonymsCCK-27-32-NH2
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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GPCR/G Protein > CCK