Fig. 1 · Structure
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(-)-Chromanol 293B
IKs Inhibitor
(-)-Chromanol 293B is a potent and selective inhibitor of the slow component of delayed rectifier potassium current (IKs). This compound is employed in research focused on antiarrhythmic therapies, providing valuable insights into cardiac ion channel regulation and its implications in arrhythmia management. It serves as a crucial tool for studying the pharmacological modulation of cardiac action potentials and the underlying mechanisms of heart rhythm disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 163163-24-4 |
| Applications | IKs Inhibitor |
| Formula | C15H20N2O4S |
| Molecular Weight | 324.40 |
| SMILES | CCS(=O)(N([C@@H]1[C@@H](O)C(C)(C)OC2=CC=C(C#N)C=C12)C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.