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CI-988 meglumin

Catalog No.: A59671
CCK2R Antagonist
CI-988 meglumin is a potent cholecystokinin 2 receptor (CCK2R) antagonist. By inhibiting CCK2R, CI-988 meglumin plays a critical role in mitigating the gastrin-mediated cardioprotective effects associated with ischemia/reperfusion injury. This compound is valuable for research in cardiac physiology and pathophysiology, particularly in studies exploring receptor signaling and myocardial stress responses.
CI-988 meglumin 130404-91-0 CCK2R Antagonist
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCI-988 meglumin is a potent cholecystokinin 2 receptor (CCK2R) antagonist. By inhibiting CCK2R, CI-988 meglumin plays a critical role in mitigating the gastrin-mediated cardioprotective effects associated with ischemia/reperfusion injury. This compound is valuable for research in cardiac physiology and pathophysiology, particularly in studies exploring receptor signaling and myocardial stress responses.
Product Information
Catalog NumA59671
FormulaC42H59N5O11
Molecular Weight809.94
CAS Number130404-91-0
SMILESOC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNC.OC(CCC(N[C@H](C1=CC=CC=C1)CNC([C@](CC2=CNC3=C2C=CC=C3)(C)NC(OC4[C@H]5C[C@H](C6)C[C@@H]4C[C@H]6C5)=O)=O)=O)=O
SynonymsPD134308 meglumin
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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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GPCR/G Protein > CCK