Fig. 1 · Structure
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Cilazapril
ACE Inhibitor
Cilazapril is an orally active prodrug targeting angiotensin-converting enzyme (ACE) and is converted into its active form, Cilazaprilat. By inhibiting ACE activity, Cilazapril effectively lowers plasma ACE levels, contributing to the regulation of blood pressure. This compound is valuable in research applications related to hypertension, including essential and renal hypertension, as well as congestive heart failure.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 88768-40-5 |
| Applications | ACE Inhibitor |
| Formula | C22H31N3O5 |
| Molecular Weight | 417.50 |
| Synonyms | Ro 31-2848 |
| SMILES | O=C([C@@H]1CCCN2N1C([C@@H](N[C@@H](CCC3=CC=CC=C3)C(OCC)=O)CCC2)=O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.