Fig. 1 · Structure
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Cintirorgon sodium
Cat. No.
A77614
CAS
2055538-47-9
RORγ Agonist
Cintirorgon sodium is a selective and orally bioavailable RORγ agonist that modulates gene expression in RORγ-expressing T lymphocytes. This compound enhances effector functions and reduces immunosuppressive mechanisms, contributing to decreased tumor growth and improved survival rates in various preclinical models. Cintirorgon sodium is a valuable tool for research applications focused on immunotherapy and cancer biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 2055538-47-9 |
| Applications | RORγ Agonist |
| Formula | C27H22F6NNaO6S |
| Molecular Weight | 625.51 |
| Synonyms | LYC-55716 sodium |
| SMILES | O=C(O[Na])C(C)(C)C[C@@H]1OC2=CC=C(C3=CC(F)=CC(OC(F)F)=C3)C=C2N(S(=O)(C4=CC=CC(C(F)(F)F)=C4)=O)C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.