Fig. 1 · Structure
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Ciprofloxacin prodrug-1
Cat. No.
A48506
CAS
2418537-98-9
Ciprofloxacin Prodrug
Ciprofloxacin prodrug-1 is an activated prodrug targeting β-lactamase-producing bacteria. It demonstrates potent antibacterial activity, with a minimum inhibitory concentration (MIC) of 63 nM against β-lactamase-expressing strains. Upon hydrolysis by β-lactamase, Ciprofloxacin prodrug-1 releases the active antibiotic Ciprofloxacin, effectively inhibiting DNA gyrase activity. This compound is valuable for investigating infections caused by drug-resistant bacteria, particularly uropathogenic Escherichia coli.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2418537-98-9 |
| Applications | Ciprofloxacin Prodrug |
| Formula | C27H28FN5O7S |
| Molecular Weight | 585.60 |
| SMILES | O=C(C(N12)=C(COC(C3=CN(C4CC4)C5=C(C=C(F)C(N6CCNCC6)=C5)C3=O)=O)CS[C@]2([H])[C@H](NC(C)=O)C1=O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.