Fig. 1 · Structure

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cis-Emodin-physcion bianthrone

PTP1B Inhibitor

cis-Emodin-physcion bianthrone is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B), demonstrating an IC50 value of 7.29 μM. This compound is crucial for research related to type 2 diabetes, where modulation of PTP1B activity may influence insulin signaling pathways and glucose homeostasis. Its inhibitory effects make it a valuable tool for investigating therapeutic strategies in metabolic disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1085706-32-6
Applications PTP1B Inhibitor
Formula C31H24O8
Molecular Weight 524.52
SMILES
O=C1C2=C(O)C=C(OC)C=C2[C@@]([C@]3([H])C4=CC(C)=CC(O)=C4C(C5=C(O)C=C(O)C=C53)=O)([H])C6=CC(C)=CC(O)=C61

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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