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Cisplatin was the first member of a class of platinum-containing anti-cancer drugs, which now also includes carboplatin and oxaliplatin. These platinum complexes react in vivo, binding to and causing crosslinking of DNA, which ultimately triggers apoptosis (programmed cell death).
Targets
| DNA synthesis (Tumor cells) | ||||
| In vitro | DMSO | 60 mg/mL (199.96 mM) | |
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 33.32 mL | 166.61 mL | 333.22 mL |
| 0.5 mM | 6.66 mL | 33.32 mL | 66.64 mL |
| 1 mM | 3.33 mL | 16.66 mL | 33.32 mL |
| 5 mM | 0.67 mL | 3.33 mL | 6.66 mL |
*The above data is based on the productmolecular weight 300.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Technical Details
| Catalog Num | A10221 |
|---|---|
| Actions | N/A |
| M. Wt | 300.1 |
| Formula | Cl2H4N2Pt |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 15663-27-1 |
| Synonyms | cisplatinum, CDDP, cis-diamminedichloroplatinum(II) |
| SMILES | N.N.Cl[Pt+2]Cl |
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Contact information
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