Fig. 1 · Structure
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CK-548
Arp2/3 Complex Inhibitor
CK-548 is an inhibitor of the Arp2/3 complex with an IC50 of 11 μM. This compound effectively inhibits HIV-1 nuclear migration and subsequent infection, making it a valuable tool for research into viral biology and host cell interactions. Its ability to disrupt actin polymerization pathways also highlights its potential in studying cytoskeletal dynamics related to various diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 388604-55-5 |
| Applications | Arp2/3 Complex Inhibitor |
| Formula | C15H11BrClNO2S |
| Molecular Weight | 384.68 |
| Synonyms | CK-0993548 |
| SMILES | O=C1N(C(SC1)C2=CC=CC(Br)=C2)C3=CC(Cl)=CC=C3O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.