CK-666

Catalog No.: A20973

Arp2/3 complex inhibitor

CK-666

CK-666 Chemical Structure

CAS NO. 442633-00-3

CK-666 is a cell-permeable inhibitor of actin-related protein Arp2/3 complex, and binds to Arp2/3 complex, stabilizes the inactive state of the complex, blocking movement of the Arp2 and Arp3 subunits into the activated filament-like (short pitch) conformation.

Availability: In stock

Package Price Qty
5 mg
$81.00
10 mg
$140.00
50 mg
$414.00
100 mg
$828.00
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Biological Activity

CK-666 is a cell-permeable inhibitor of actin-related protein Arp2/3 complex, and binds to Arp2/3 complex, stabilizes the inactive state of the complex, blocking movement of the Arp2 and Arp3 subunits into the activated filament-like (short pitch) conformation.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.75 mL 168.73 mL 337.45 mL
0.5 mM 6.75 mL 33.75 mL 67.49 mL
1 mM 3.37 mL 16.87 mL 33.75 mL
5 mM 0.67 mL 3.37 mL 6.75 mL

*The above data is based on the productmolecular weight 296.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A20973
Actions Inhibitor
CAS No. 442633-00-3
Formula C18H17FN2O
M. Wt 296.34
Purity >98%
Synonyms CK666, CK 666
SMILES O=C(NCCC1=C(C)NC2=C1C=CC=C2)C3=CC=CC=C3F
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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