Cl-HIBO is a highly selective agonist for the GluR1 and GluR2 subtypes of AMPA receptors, exhibiting EC50 values of 4.7 μM and 1.7 μM, respectively. This compound demonstrates potent activity as an AMPA receptor agonist with an IC50 of 0.22 μM. Additionally, Cl-HIBO displays desensitizing properties, making it a valuable tool for research in neuropharmacology and studies of synaptic transmission.
Cl-HIBO is a highly selective agonist for the GluR1 and GluR2 subtypes of AMPA receptors, exhibiting EC50 values of 4.7 μM and 1.7 μM, respectively. This compound demonstrates potent activity as an AMPA receptor agonist with an IC50 of 0.22 μM. Additionally, Cl-HIBO displays desensitizing properties, making it a valuable tool for research in neuropharmacology and studies of synaptic transmission.
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