Fig. 1 · Structure

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Cleomiscosin A

TNF-alpha Inhibitor

Cleomiscosin A is a coumarino-lignoid that functions as a TNF-alpha inhibitor. It effectively reduces TNF-alpha secretion in mouse peritoneal macrophages, making it a valuable reagent for research focused on inflammation and immune responses. This compound has potential applications in studying the modulation of cytokine activity and the development of anti-inflammatory therapies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 76948-72-6
Applications TNF-alpha Inhibitor
Formula C20H18O8
Molecular Weight 386.35
SMILES
COC1=CC(C=CC2=O)=C(O2)C3=C1O[C@H](C4=CC(OC)=C(O)C=C4)[C@@H](CO)O3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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