Fig. 1 · Structure
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Cletoquine oxalate
Antiviral Agent
Cletoquine oxalate is an antiviral agent and a prominent active metabolite of Hydroxychloroquine, formed in the liver by several cytochrome P450 isoenzymes, including CYP2D6, CYP3A4, CYP3A5, and CYP2C8. This compound exhibits antiviral activity specifically against the chikungunya virus (CHIKV) and offers antimalarial properties. Additionally, Cletoquine oxalate may have therapeutic applications in the treatment of autoimmune diseases, making it a valuable reagent for related research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 14142-64-4 |
| Applications | Antiviral Agent |
| Formula | C18H24ClN3O5 |
| Molecular Weight | 397.85 |
| Synonyms | Desethylhydroxychloroquine oxalate |
| SMILES | CC(NC1=CC=NC2=CC(Cl)=CC=C12)CCCNCCO.O=C(O)C(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.