Fig. 1 · Structure
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Cletoquine
Antiviral Agent
Cletoquine, an active metabolite of Hydroxychloroquine, functions primarily as an antiviral agent. It is synthesized in the liver through the action of CYP2D6, CYP3A4, CYP3A5, and CYP2C8 isoenzymes. Cletoquine exhibits significant activity against the chikungunya virus (CHIKV) while also demonstrating antimalarial properties. This compound holds potential for therapeutic applications in autoimmune diseases, contributing to research efforts in virology and immunology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 4298-15-1 |
| Applications | Antiviral Agent |
| Formula | C16H22ClN3O |
| Molecular Weight | 307.82 |
| Synonyms | Desethylhydroxychloroquine |
| SMILES | CC(NC1=CC=NC2=CC(Cl)=CC=C12)CCCNCCO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.