Clomipramine-d3 hydrochloride is a deuterium-labeled analog of Clomipramine hydrochloride, primarily acting as an inhibitor of the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT) with Ki values of 0.14 nM, 54 nM, and 3 nM, respectively. This stable isotope-labeled compound is valuable for pharmacokinetic studies, metabolic profiling, and tracer experiments in neuroscience research. Its specificity and potency make it an essential reagent for investigating the pharmacological effects of antidepressants and their mechanisms of action within the central nervous system.
Clomipramine-d3 hydrochloride is a deuterium-labeled analog of Clomipramine hydrochloride, primarily acting as an inhibitor of the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT) with Ki values of 0.14 nM, 54 nM, and 3 nM, respectively. This stable isotope-labeled compound is valuable for pharmacokinetic studies, metabolic profiling, and tracer experiments in neuroscience research. Its specificity and potency make it an essential reagent for investigating the pharmacological effects of antidepressants and their mechanisms of action within the central nervous system.
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