Fig. 1 · Structure
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CM-352
MMPs Inhibitor
CM-352 is a potent inhibitor of matrix metalloproteinases (MMPs), specifically targeting MMP-3 with an IC50 of 15 nM and MMP-10 with an IC50 of 12 nM. This compound exhibits significant antifibrinolytic activity, with an EC50 of 0.7 nM, effectively prolonging blood coagulation time. CM-352 is valuable for research applications focused on anti-bleeding strategies and the modulation of extracellular matrix dynamics.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1664361-37-8 |
| Applications | MMPs Inhibitor |
| Formula | C24H29N3O6S |
| Molecular Weight | 487.57 |
| SMILES | O=S([C@]1(CC2(CCNCC2)CC1)C(NO)=O)(C3=CC=C(C=C3)OC4=CC=C(C=C4)C(NC)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.