Fig. 1 · Structure
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CM764
Sigma Receptor Activator
CM764 is a sigma receptor activator, exhibiting Ki values of 86.6 nM for the sigma-1 receptor and 3.5 nM for the sigma-2 receptor. This compound increases cytoplasmic calcium levels, enhances NAD+/NADH and ATP production, and reduces reactive oxygen species (ROS) concentration. CM764 is relevant for studies exploring sigma receptor pathways and their implications in cellular metabolism and oxidative stress.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 1350296-29-5 |
| Applications | Sigma Receptor Activator |
| Formula | C23H27FN4O3 |
| Molecular Weight | 426.48 |
| SMILES | O=C1OC2=CC(C(C)=O)=CC=C2N1CCCCN3CCN(C4=CC=C(F)C=C4N)CC3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.