CMP233

Catalog No.: A68809
TRPM4 Antagonist
CMP233 is a potent TRPM4 antagonist with an IC50 value of 0.15 μM. This compound is valuable in the study of neurodegenerative disorders, providing insights into the role of TRPM4 channels in various pathological conditions. Its high specificity and efficacy make it a key tool for researchers investigating TRPM4-mediated signaling pathways.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCMP233 is a potent TRPM4 antagonist with an IC50 value of 0.15 μM. This compound is valuable in the study of neurodegenerative disorders, providing insights into the role of TRPM4 channels in various pathological conditions. Its high specificity and efficacy make it a key tool for researchers investigating TRPM4-mediated signaling pathways.
Product Information
Catalog NumA68809
FormulaC16H14BrNO3
Molecular Weight348.19
CAS Number307001-06-5
SMILESO=C(O)C1=CC(Br)=CC=C1NC(CCC2=CC=CC=C2)=O
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