Biological Activity
CMPD-1 is a non-ATP-competitive, selective inhibitor of p38α-mediated MK2a (mitogen-activated protein kinase-2a) phosphorylation (apparent Ki = 330 nM).
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 28.62 mL | 143.1 mL | 286.2 mL |
0.5 mM | 5.72 mL | 28.62 mL | 57.24 mL |
1 mM | 2.86 mL | 14.31 mL | 28.62 mL |
5 mM | 0.57 mL | 2.86 mL | 5.72 mL |
*The above data is based on the productmolecular weight 349.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A16040 |
---|---|
Actions | Inhibitor |
M. Wt | 349.4 |
Formula | C22H20FNO2 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 41179-33-3 |
Synonyms | CMPD1, CMPD 1 |
SMILES | FC1=CC=CC=C1C2=CC=C(C=C2)CCCC(NC(C=C3)=CC=C3O)=O |
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