Fig. 1 · Structure

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Coblopasvir dihydrochloride

NS5A Inhibitor

Coblopasvir dihydrochloride is a pangenotypic inhibitor of the non-structural protein 5A (NS5A) involved in hepatitis C virus replication. This reagent exhibits potent antiviral activity against hepatitis C, making it a valuable tool for studying chronic hepatitis C virus infection and the development of therapeutic strategies. Its mechanism of action provides insights into NS5A's role in viral lifecycle and resistance.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1966138-53-3
Applications NS5A Inhibitor
Formula C41H52Cl2N8O8
Molecular Weight 855.81
Synonyms KW-136 dihydrochloride
SMILES
O=C(N[C@H](C(N1[C@@H](CCC1)C2=NC(C3=CC=C(C=C3)C4=C5OCOC5=C(C=C4)C6=CNC([C@H]7N(CCC7)C([C@H](C(C)C)NC(OC)=O)=O)=N6)=CN2)=O)C(C)C)OC.[H]Cl.[H]Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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