Colterol hydrochloride-d9

Catalog No.: A58470
Stable Isotope
Colterol hydrochloride-d9 is a deuterium-labeled derivative of Colterol hydrochloride, a selective agonist for adrenergic receptors. It demonstrates significant binding affinity for both the β1-adrenoreceptor, with an IC50 of 645 nM, and the β2-adrenoreceptor, with an IC50 of 147 nM. This compound is primarily utilized in research focusing on adrenergic signaling and has potential applications as a bronchodilator in respiratory studies.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionColterol hydrochloride-d9 is a deuterium-labeled derivative of Colterol hydrochloride, a selective agonist for adrenergic receptors. It demonstrates significant binding affinity for both the β1-adrenoreceptor, with an IC50 of 645 nM, and the β2-adrenoreceptor, with an IC50 of 147 nM. This compound is primarily utilized in research focusing on adrenergic signaling and has potential applications as a bronchodilator in respiratory studies.
Product Information
Catalog NumA58470
FormulaC12H11D9ClNO3
Molecular Weight270.80
CAS Number2714484-83-8
SMILESOC1=C(C=CC(C(O)CNC(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=C1)O.Cl
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