Fig. 1 · Structure
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Coronastat
Anti-infection Agent
Coronastat is a potent inhibitor of the SARS-CoV-2 3CL protease, a crucial enzyme involved in the viral replication and maturation cycle. By targeting this protease, Coronastat demonstrates significant anti-infection activity against SARS-CoV-2. This compound is valuable for research focused on developing small molecule therapeutics for COVID-19 and offers insights into coronavirus biology and pathogenesis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2922281-15-8 |
| Applications | Anti-infection Agent |
| Formula | C22H29F3N3NaO8S |
| Molecular Weight | 575.53 |
| Synonyms | NK01-63 |
| SMILES | OC(S(=O)(O[Na])=O)[C@H](C[C@@H]1CCNC1=O)NC([C@H](CC(C)C)NC(OCC2=CC(C(F)(F)F)=CC=C2)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.