Cortistatin-8 (CST-8; PCFWKTCK) is a synthetic analogue of the neuropeptide cortistatin that acts as an antagonist of the ghrelin receptor (GHS-R1a). This compound counteracts the effects of ghrelin on gastric acid secretion and influences growth hormone release from somatotroph cells. With no binding affinity for somatostatin receptors (SST-R), Cortistatin-8 is specifically designed for research applications investigating the modulation of ghrelin signaling both in vitro and in vivo.
Cortistatin-8 (CST-8; PCFWKTCK) is a synthetic analogue of the neuropeptide cortistatin that acts as an antagonist of the ghrelin receptor (GHS-R1a). This compound counteracts the effects of ghrelin on gastric acid secretion and influences growth hormone release from somatotroph cells. With no binding affinity for somatostatin receptors (SST-R), Cortistatin-8 is specifically designed for research applications investigating the modulation of ghrelin signaling both in vitro and in vivo.
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