Fig. 1 · Structure

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Corybulbine

ALR2 Inhibitor

Corybulbine is an alkaloid derived from the methanolic extract of Corydalis ternata and functions as an aldose reductase (ALR2) inhibitor. It exhibits potential therapeutic effects in the treatment of diabetic complications by modulating glucose metabolism and preventing the accumulation of sorbitol. This compound serves as a valuable tool for research into the mechanisms underlying diabetes and related metabolic disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 518-77-4
Applications ALR2 Inhibitor
Formula C21H25NO4
Molecular Weight 355.43
SMILES
C[C@@H]1[C@]2([H])C3=CC(OC)=C(O)C=C3CCN2CC4=C(OC)C(OC)=CC=C41

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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