Fig. 1 · Structure

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CP 461

Apoptotic Antineoplastic Agent

CP-461 is a selective apoptotic antineoplastic agent that targets tubulin at the colchicine binding site. It induces apoptosis in cancer cells through microtubule destabilization, offering potential therapeutic benefits in oncology research. CP-461 provides a valuable tool for studying cell death pathways and assessing the efficacy of targeted cancer treatments.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 227619-96-7
Applications Apoptotic Antineoplastic Agent
Formula C25H22ClFN2O
Molecular Weight 420.91
Synonyms OSI-461
SMILES
O=C(NCC1=CC=CC=C1)CC(C2=CC(F)=CC=C2/3)=C(C)C3=C\C4=CC=NC=C4.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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